Identification and characterization of RNA polymerase sigma factor from Micrococcus luteus.

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Identification and characterization of RNA polymerase sigma factor from Micrococcus luteus.

The promoters of Micrococcus luteus, a bacterium whose chromosomal DNA has a high G + C content (74%), diverge from the consensus prokaryotic promoter in having GC-rich DNA sequences at less important positions (Nakayama, M., Fujita, N., Ohama, T., Osawa, S., and Ishihama, A. (1989) Mol. Gen. Genet. 218, 384-389). In order to compare the promoter selectivity of RNA polymerase between M. luteus ...

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Purification and Characterization of an w Protein from Micrococcus luteus*

An w protein capable of a concerted breaking and rejoining of DNA backbone bonds has been purified from Micrococcus luteus to homogeneity. The protein is a single polypeptide with a molecular weight of 120,000. It catalyzes the removal of superhelical turns from a highly negatively twisted DNA efficiently. The reaction requires Mg2+. In a medium containing 0.1 M K+, the enzyme acts in distribut...

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Sigma factor displacement from RNA polymerase during Bacillus subtilis sporulation.

As Bacillus subtilis proceeds through sporulation, the principal vegetative cell sigma subunit (sigma(A)) persists in the cell but is replaced in the extractable RNA polymerase (RNAP) by sporulation-specific sigma factors. To explore how this holoenzyme changeover might occur, velocity centrifugation techniques were used in conjunction with Western blot analyses to monitor the associations of R...

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DNA-relaxing enzyme from Micrococcus luteus.

A DNA-relaxing enzyme which catalyzes the conversion of superhelical DNA to a non-superhelical covalently closed form has been purified from Micrococcus luteus to near homogeneity by two chromatographic steps. The enzyme is a single polypeptide chain. As determined by sodium dodecyl sulfate - polyacrylamide gel electrophoresis and gel filtration on Sephadex G 150, the molecular weight is 115,00...

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Transcription termination factor Rho is essential for Micrococcus luteus.

The growth of Micrococcus luteus, a soil microorganism that belongs to the high-G+C gram-positive phylogenetic group, is prevented by bicyclomycin, an antibiotic that inhibits the activity of the M. luteus transcription termination factor Rho. A mutant that can grow in 0.3 mM bicyclomycin has a Rho that is insensitive to bicyclomycin and has the single amino acid residue change of Asp474 to Gly...

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ژورنال

عنوان ژورنال: Journal of Biological Chemistry

سال: 1991

ISSN: 0021-9258

DOI: 10.1016/s0021-9258(18)49934-6